Exploring breathing pattern irregularity with projection-based method
Exploring breathing pattern irregularity with projection-based method
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DOI：
10.1118/1.2207253
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发表时间：
2006-07-01
期刊：
影响因子：
3.8
通讯作者：
Sonke, Jan-Jakob
中科院分区：
文献类型：
--
作者：
Ruan, Dan;Fessler, Jeffrey A.;Sonke, Jan-Jakob
由于呼吸引起的器官运动的准确描述对于放射治疗规划是高度期望的。本文提出了一个指数，量化的不规则性的信号相关的呼吸运动。该方法的工作原理是找到最适合信号样本的周期性带限信号，然后计算均方根（RMS）残差。拟合的信号本身可用于治疗计划。使用描述来自12名患者的振幅-时间关系（RPM，Varian）的临床数据，我们将所提出的指数与来自各种治疗计划方案的相关指标相关联。仿真结果表明，与所有考虑的处理方法的合理匹配，表明所提出的不规则性指数是适合于各种处理方法。与之前研究的用于呼吸模式模型的修正余弦函数相比，所提出的方法更具代表性、灵活性和计算效率。(C)2006年美国医学物理学家协会。
Accurate descriptions of organ motion due to breathing are highly desirable for radiation treatment planning. This paper proposes an index that quantifies the irregularity of a signal related to respiratory motion. The method works by finding the periodic band-limited signal that best fits the signal samples, and then computing the root mean squared (RMS) residual error. The fitted signal itself may be useful for treatment planning. Using clinical data describing amplitude-time relationships (RPM, Varian) from twelve patients, we correlated the proposed index against relevant metrics from various treatment planning schemes. Simulation results demonstrate a reasonable match with all treatment methods considered, suggesting that the proposed irregularity index is suitable for a variety of treatment methods. Compared to the modified cosine function, which was investigated previously for breathing pattern models, the proposed approach is more representative, flexible, and computationally efficient. (C) 2006 American Association of Physicists in Medicine.