Outbreak of Crimean-Congo haemorrhagic fever in Quetta, Pakistan: contact tracing and risk assessment
Outbreak of Crimean-Congo haemorrhagic fever in Quetta, Pakistan: contact tracing and risk assessment
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DOI：
10.1046/j.1365-3156.1998.00318.x
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发表时间：
1998-11-01
影响因子：
3.3
通讯作者：
Fisher-Hoch, S
中科院分区：
文献类型：
--
作者：
Altaf, A;Luby, S;Fisher-Hoch, S
1994年12月，在巴基斯坦奎达的一家私人医院，3名保健工作者在为一名出血病人做手术后感染了克里米亚-刚果出血热，病人后来死亡。我们进行了一项回顾性研究，以确定接触者之间的传播风险。50名接触者为抗体测试提供了血液，并回答了有关接触的问题。四分之二的人暴露于皮肤，五分之一的人皮肤接触感染了CCHF。皮肤接触的人是一名外科医生，他在手术中撕裂了手套，注意到手上有血，但没有伤口。皮肤接触血液以外的体液者（0/4）、皮肤接触患者者（0/16）、身体接触患者者（0/21）均未检出抗CCHF抗体或CCHF病例。3名索引病例亲属报告称，尽管10名家庭成员有皮肤暴露，但均未发生CCHF。家人拒绝验血。通过重点避免卫生工作者接触血液，可以限制资源有限环境中的CCHF传播。
In December 1994 in a private hospital in Quetta, Pakistan, 3 health-workers contracted Crimean-Congo haemorrhagic fever (CCHF) after surgery on a bleeding patient who later died. We conducted a retrospective study to determine transmission risks among contacts. Fifty contacts gave blood for antibody tests and answered questions about exposure. Two of four people exposed percutaneously and one of five with cutaneous exposure contracted CCHF The person with cutaneous exposure was a surgeon who tore his glove during surgery and noted blood on his hand but no cut. There were no anti-CCHF antibodies or CCHF cases among persons whose skin came into contact with body fluids other than blood (0/4), who had skin-to-skin contact (0/16) with patients or were physically close to them (0/21). Three index case relatives reported that although 10 family members had cutaneous exposure, none developed CCHF. The family refused blood tests. CCHF transmission in resource-constrained settings can be limited by focusing on avoiding health worker contact with blood.