WHO IS AT RISK FOR ONGOING DIZZINESS AND PSYCHOLOGICAL STRAIN AFTER A VESTIBULAR DISORDER?
WHO IS AT RISK FOR ONGOING DIZZINESS AND PSYCHOLOGICAL STRAIN AFTER A VESTIBULAR DISORDER?
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DOI：
10.1016/j.neuroscience.2009.09.034
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发表时间：
2009-12-29
期刊：
影响因子：
3.3
通讯作者：
Dieterich, M.
中科院分区：
文献类型：
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作者：
Best, C.;Tschan, R.;Dieterich, M.
患有前庭眩晕综合征的患者经常遭受焦虑和抑郁，而患有精神障碍的患者通常经历主观不稳定、头晕或眩晕。因此，假设前庭系统可能与情绪处理系统相互关联。目前研究的目的是通过将前庭症状和精神症状与病程超过1年相关联来评估这一假说。这项跨学科、前瞻性、纵向研究共纳入68名急性前庭眩晕综合征患者。对良性阵发性位置性眩晕(BPPV，n=19)、急性前庭神经炎(VN，n=14)、前庭偏头痛(Vm，n=27)和梅尼埃病(MD，n=8)患者进行比较。所有患者均于1年中的5个不同时间段(T0~T4)进行神经及神经耳科检查，并填写标准化自评量表，包括眩晕症状量表(VSS)、眩晕残障问卷(VHQ)及症状自评量表(GSI、SCL-90R)。VM患者出现“眩晕及相关症状”(VSS-VER)、“躯体焦虑和自主神经觉醒”(VSS-AA)和“眩晕致残”(VHQ)的比例明显高于其他患者(P
Patients with vestibular vertigo syndromes often suffer from anxiety and depression, whereas patients with psychiatric disorders often experience subjective unsteadiness, dizziness, or vertigo. Thus, it has been hypothesized that the vestibular system may be interlinked with the emotion processing systems. The aim of the current study was to evaluate this hypothesis by correlating vestibular and psychiatric symptoms with the course of the disease over 1 year. This interdisciplinary, prospective, longitudinal study included a total of 68 patients with acute vestibular vertigo syndromes. Four subgroups of patients with benign paroxysmal positioning vertigo (BPPV, n=19), acute vestibular neuritis (VN, n=14), vestibular migraine (VM, n=27), or Meniere's disease (MD, n=8) were compared. All patients underwent neurological and neuro-otological examinations and filled out standardized self-report inventories including the Vertigo Symptom Scale (VSS), the Vertigo Handicap Questionnaire (VHQ) and the Symptom Checklist 90R (GSI, SCL-90R) at five different times (T0-T4) in the course of I year. VM patients experienced significantly more "vertigo and related symptoms" (VSS-VER), "somatic anxiety and autonomic arousal" (VSS-AA), and "vertigo induced handicap" (VHQ) than all other patients (P