The effect of physical stress on gastric secretion and pancreatic polypeptide levels in man.

The effect of physical stress on gastric secretion and pancreatic polypeptide levels in man.
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身体压力对人体胃分泌和胰多肽水平的影响。

DOI:
10.1080/00365521.1984.12005807
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发表时间:
1984
影响因子:
1.9
通讯作者:
R. Jorde
R. Jorde
中科院分区:
医学4区
文献类型:
--
作者:
O. Oktedalen;I. Guldvog;P. Opstad;A. Berstad;D. Gedde;R. Jorde

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12 名健康受试者接受了为期 4 天的高强度体育锻炼、热量供应不足和严重睡眠不足。在此应激期后立即测量基础酸输出(BAO)、假喂养诱导的酸输出(MAOsh)和五肽胃泌素刺激的酸输出(MAOpg),并在几周后进行的对照实验中进行测量。应激导致 BAO 中位数增加三倍,MAOsh 增加(p 小于 0.05),但扣除基础值后,MAOsh 并未显着升高。 MAOpg 没有变化。与酸相反,胃蛋白酶的输出不受压力的影响。应激后,血清中的人胰多肽(hPP)水平增加了一倍。应激后改良假喂养诱导的综合 hPP 反应高于对照实验 (p = 0.02)。结果表明,身体应激对胃酸和胃蛋白酶的分泌有单独的影响。
Twelve healthy subjects were exposed to a 4-day period of hard physical exercise, calorie supply deficiency, and severe sleep deprivation. The basal acid output (BAO), the sham-feeding-induced acid output (MAOsh), and the pentagastrin-stimulated acid output (MAOpg) were measured immediately after this stress period and in a control experiment performed several weeks later. The stress induced a threefold increase in the median BAO and an increase (p less than 0.05) in the MAOsh, which, however, was not significantly elevated when basal-subtracted. MAOpg was unchanged. In contrast to acid, pepsin output was not influenced by stress. The human pancreatic polypeptide (hPP) level in serum increased twofold after the stress. The integrated hPP response induced by modified sham feeding was higher (p = 0.02) after the stress than in the control experiment. The results show that physical stress has separate influence on the gastric secretion of acid and pepsin.
假喂养对健康受试者和十二指肠溃疡患者胃酸分泌的影响:一些溃疡患者基础迷走神经张力增加的证据。
DOI: --
发表时间: 1980
期刊: Gastroenterology
影响因子: 29.4
作者:
Feldman,M;Richardson,CT;Fordtran,JS
通讯作者: Fordtran,JS