Role of the endogenous opioid system on the neuropsychopharmacological effects of ethanol: New insights about an old question
Role of the endogenous opioid system on the neuropsychopharmacological effects of ethanol: New insights about an old question
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DOI：
10.1097/01.alc.0000174913.60384.e8
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发表时间：
2005-08-01
影响因子：
3.2
通讯作者：
Cowen, MS
中科院分区：
文献类型：
--
作者：
Sanchis-Segura, C;Grisel, JE;Cowen, MS
本文介绍了研讨会的会议记录“内源性阿片类药物和自愿乙醇消费：我们从敲除小鼠中学到了什么？“2004年9月/10月在德国海德堡/曼海姆举行的国际酗酒问题生物医学研究学会会议上提出。会议的组织者和主席是迈克尔·S。Cowen和Carles Sanchis-Segura。主要内容如下：（1）酒精对阿片系统的调节：嗜酒精和不嗜酒精菌株的比较。内源性阿片类物质和酒精：来自微透析和基因敲除小鼠的教训。福斯特橄榄;（3）从神经化学到神经解剖学：下丘脑弓状核是乙醇-阿片类药物相互作用的主要部位（Carles Sanchis-Segura）;（4）转基因小鼠对乙醇的敏感性受β-内啡肽的调节（Judy E. Grisel，阿曼达J.罗伯茨和乔治F.（5）μ-阿片受体调节急性乙醇敏感性和乙醇戒断严重性，Sandra Ghozland。
This article presents the proceedings of the symposium "Endogenous Opioids and Voluntary Ethanol Consumption: What Have We Learnt From Knock-out Mice?" presented at the meeting of the International Society for Biomedical Research on Alcoholism held in Heidelberg/Mannheim, Germany, in September/October 2004. The organizers and chairpersons were Michael S. Cowen and Carles Sanchis-Segura. The presentations were as follows: (1) Regulation of the Opioid System by Alcohol: Comparison of Alcohol-Preferring and -Nonpreferring Strains by Michael S. Cowen; (2) Endogenous Opioids and Alcohol: Lessons From Microdialysis and Knock-out Mice by M. Foster Olive; (3) From Neurochemistry to Neuroanatomy: The Hypothalamic Arcuate Nucleus as a Main Site for Ethanol-Opioids Interaction by Carles Sanchis-Segura; (4) Sensitivity to Ethanol Is Modulated by beta-Endorphin in Transgenic Mice by Judy E. Grisel, Amanda J. Roberts, and George F. Koob; and (5) The mu-Opioid Receptor Modulates Acute Ethanol Sensitivity and Ethanol Withdrawal Severity by Sandra Ghozland.