CHLORINATED HYDROCARBONS IN ADIPOSE-TISSUE OF INFANTS AND TODDLERS - INVENTORY AND STUDIES ON THEIR ASSOCIATION WITH INTAKE OF MOTHERS MILK
CHLORINATED HYDROCARBONS IN ADIPOSE-TISSUE OF INFANTS AND TODDLERS - INVENTORY AND STUDIES ON THEIR ASSOCIATION WITH INTAKE OF MOTHERS MILK
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DOI：
10.1007/bf00540242
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发表时间：
1984-01-01
影响因子：
3.6
通讯作者：
HOFMANN, U
中科院分区：
文献类型：
--
作者：
NIESSEN, KH;RAMOLLA, J;HOFMANN, U
对34名婴儿、14名两岁儿童和2名年龄较大的儿童的脂肪组织中氯代烃和多氯联苯（PCB）浓度进行了测定。在生命的头2年中检测到的最高平均浓度是多氯联苯（0.67 ppm），其次是滴滴涕（0.57 ppm）、六氯苯（0.23 ppm）和六氯环己烷（0.15 ppm）。六氯苯和多氯联苯的浓度是高度工业化国家的特征，在母亲为西德人的儿童中的浓度要比母亲为土耳其人的儿童高得多。所有单一调查值均低于西德国成人的平均值，但许多仍高于世界其他地区成人的平均浓度。母乳摄入量高的儿童和母乳摄入量低的儿童的分类显示，母乳摄入量与母乳摄入量之间存在高度显著的关联。高摄入量儿童脂肪组织中有机卤素浓度显著高于低摄入量儿童。需要开发进一步的方法来减少环境有机卤素污染源，并研究这些有机卤素对儿童健康的可能致病作用。
Chlorinated hydrocarbon and polychlorinated biphenyl (PCB) concentrations were determined in adipose tissue from 34 infants, 14 children in the 2nd yr of life and 2 older children. The highest mean concentration detected during the first 2 yr of life was for PCB (0.67 ppm), followed by DDT (0.57 ppm), HCB (hexachlorobenzene) (0.23 ppm) and HCH (hexachlorocyclohexane isomers) (0.15 ppm). HCB and PCB concentrations, which are characteristic of highly industrialized countries, were considerably higher in children of West German mothers than in those of Turkish mothers. All single investigated values were lower than the mean values for adults in West Germany, but many were still higher than mean concentrations for adults in other parts of the world. A breakdown into children with high mothers'' milk intake and those with low intake showed a highly significant association with the quantity of mothers'' milk consumed. Organohalogen concentration in the adipose tissue of children with high intake was significantly higher than in those with low intake. Development of further ways to reduce environmental organohalogen contamination sources and the study of the possible pathogenetic effect of these organohalogens on children''s health is needed.