Fundamental issues in mosquito surveillance for arboviral transmission
Fundamental issues in mosquito surveillance for arboviral transmission
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DOI：
10.1016/j.trstmh.2008.03.019
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发表时间：
2008-08-01
影响因子：
2.2
通讯作者：
Novak, Robert J.
中科院分区：
文献类型：
--
作者：
Gu, Weidong;Unnasch, Thomas R.;Novak, Robert J.
以西尼罗河病毒（WNV）在美国的传播为例，蚊虫感染虫媒病毒具有明显的时空变异性，因此需要采取适应性策略进行蚊子取样、池筛选和数据分析。目前缺乏可靠和一致的风险暴露措施，这可能会影响监测数据的比较。基于定量推理，我们严格审查了有关蚊子采样设计和传播强度估计的基本问题。提出了两种监测战略，每一种战略都有不同的重点，即有针对性地监测以发现低蚊子感染率，并广泛监测以评估蚊子高感染水平的风险暴露。我们强烈建议使用体现蚊子数量和感染率的指标作为风险暴露的措施。长时间和大范围地区监测数据的汇总模糊了虫媒病毒的局灶性传播模式。我们相信，这些定量问题，一旦通过蚊子监测项目得到解决，可以提高虫媒病毒传播的流行病学情报。(c) 2008年皇家热带医学和卫生学会。Elsevier Ltd.出版。版权所有。
Marked spatiotemporal variabilities in mosquito infection of arboviruses, exemplified by the transmission of West Nile virus (WNV) in America, require adaptive strategies for mosquito sampling, pool screening and data analyses. Currently there is a lack of reliable and consistent measures of risk exposure, which may compromise comparison of surveillance data. Based on quantitative reasoning, we critically examined fundamental issues regarding mosquito sampling design and estimation of transmission intensity. Two surveillance strategies were proposed, each with a distinct focus, i.e. targeted surveillance for detection of tow rates of mosquito infection and extensive surveillance for evaluation of risk exposure with high levels of mosquito infection. We strongly recommend the use of indicators embodying both mosquito abundance and infection rates as measures of risk exposure. Aggregation of surveillance data over tong periods of time and across broad areas obscures patterns of focal arboviral transmission. We believe that these quantitative issues, once addressed by mosquito surveillance programs, can improve the epidemiological intelligence of arbovirus transmission. (c) 2008 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.