Promising use of minocycline augmentation with clozapine in treatment- resistant schizophrenia
Promising use of minocycline augmentation with clozapine in treatment- resistant schizophrenia
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DOI：
10.1177/0269881114527358
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发表时间：
2014-07-01
影响因子：
4.1
通讯作者：
Husain, N.
中科院分区：
文献类型：
--
作者：
Qurashi, I.;Collins, J. D.;Husain, N.
Treatment-resistant schizophrenia is a major health problem in the UK with the majority of patients treated with clozapine. In up to 70% of cases there is only a partial response to clozapine with continuing refractory symptoms. We describe two cases in a UK mental health service where minocycline was found to be useful and well tolerated as an augmentation agent with clozapine in the improvement of previously resistant positive and negative symptoms.
