The first example of anomeric glycoconjugation to phthalocyanines
The first example of anomeric glycoconjugation to phthalocyanines
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DOI：
10.1016/j.tetlet.2006.03.029
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发表时间：
2006-05-08
影响因子：
1.8
通讯作者：
Ziegler, T
中科院分区：
文献类型：
--
作者：
Alvarez-Mico, X;Calvete, MJF;Ziegler, T
本文首次采用糖苷化方法制备了外周葡萄糖取代锌（II）酞菁6，并对其进行了表征，该方法可采用经典的Pc模板化学方法与无保护的邻苯二腈4进行连接。酞菁6的产率高，在水中的溶解度高，这是潜在生物应用的首要条件。(c) 2006 Elsevier Ltd.版权所有。
Preparation and characterization of peripherally glucose substituted zinc(II) phthalocyanine 6, linked via the anomerie carbon through a novel glycosidation method is reported for the first time, for which classical Pc template chemistry with the unprotected phthalonitrile 4 could be used. Phthalocyanine 6 was formed in high yield and is displaying a high solubility in water as a primary condition for a potential biological application. (c) 2006 Elsevier Ltd. All rights reserved.