Animal Research: Interdisciplinary Perspectives on the History and Future of the 3Rs
Animal Research: Interdisciplinary Perspectives on the History and Future of the 3Rs
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动物研究：3R 的历史和未来的跨学科视角
DOI：
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发表时间：
2018
期刊：
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通讯作者：
R. G. Kirk
中科院分区：
文献类型：
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作者：
G. Davies;B. Greenhough;R. G. Kirk
3R 原则（替代、改进和减少）强烈影响了对进行更人道的动物研究的方法的讨论以及这一有争议的技术科学领域的监管。本期特刊通过埃克塞特大学五个地理系、英国埃克塞特地理与环境学院、牛津大学环境中心、牛津大学应用生物伦理学中心、诺丁汉大学兽医与科学学院、莱斯特郡萨顿博宁顿校区、英国科学、技术与医学史中心、曼彻斯特大学生物、医学与健康学院，回顾了3R原则的起源，英国曼彻斯特通讯作者：盖尔·戴维斯 (Gail Davies)，埃克塞特大学地理系，地址：Amory Building, Rennes Drive, Exeter EX4 4RJ, UK。电子邮件：g.f.davies@exeter.ac.uk 科学、技术与人类价值 2018 年，卷。 43(4) 603-621 a 作者 2018 年重印和许可：sagepub.com/journalsPermissions.nav DOI：10.1177/0162243918757034 Journals.sagepub.com/home/sth 论文探讨了它在实践中如何制定和受到挑战，并对其未来进行了批判性思考。三个主题将本期特刊中的论文联系起来。这些是（1）在研究中使用和照顾动物的人所扮演的多重角色，（2）“重要的情感”在实验动物实践中跨物种和空间的分布，以及（3）“护理文化”在动物研究中日益重要。
The principles of the 3Rs—replacement, refinement, and reduction— strongly shape discussion of methods for performing more humane animal research and the regulation of this contested area of technoscience. This special issue looks back to the origins of the 3Rs principles through five Department of Geography, University of Exeter, Exeter, UK School of Geography and the Environment, Oxford University Centre for the Environment, University of Oxford, Oxford, UK Centre for Applied Bioethics, School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire, UK Centre for the History of Science, Technology and Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK Corresponding Author: Gail Davies, Department of Geography, University of Exeter, Amory Building, Rennes Drive, Exeter EX4 4RJ, UK. Email: g.f.davies@exeter.ac.uk Science, Technology, & Human Values 2018, Vol. 43(4) 603-621 a The Author(s) 2018 Reprints and permission: sagepub.com/journalsPermissions.nav DOI: 10.1177/0162243918757034 journals.sagepub.com/home/sth papers that explore how it is enacted and challenged in practice and that develop critical considerations about its future. Three themes connect the papers in this special issue. These are (1) the multiplicity of roles enacted by those who use and care for animals in research, (2) the distribution of “feelings that matter” across species and spaces of laboratory animal practice, and (3) the growing importance of “cultures of care” in animal research.