Laryngoscopic detection of pharyngeal carcinoma in situ with narrowband imaging
Laryngoscopic detection of pharyngeal carcinoma in situ with narrowband imaging
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DOI：
10.1097/01.mlg.0000204304.38797.34
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发表时间：
2006-04-01
期刊：
影响因子：
2.6
通讯作者：
Sasaki, S
中科院分区：
文献类型：
--
作者：
Watanabe, A;Tsujie, H;Sasaki, S
目的：窄带成像(NBI)是一种新的光学技术，它通过在视频内窥镜系统中使用窄带滤光片来提高内窥镜对组织的诊断能力。本研究的目的是验证NBI系统在口咽部和下咽部进行内窥镜筛查的有效性。方法：本研究于2005年7月至2005年8月期间进行。在此期间，217例食道癌患者在日本札幌庆裕医院耳鼻喉科接受了口咽和下咽的NBI系统的内窥镜筛查。结果：在217例患者中，NBI系统共发现6个浅表病变，其中口咽1个，下咽5个。在传统的电子内窥镜下，6个病灶中有4个因直径小于或等于5 mm而难以辨认。NBI切面比传统的电子内窥镜切面更有利于识别浅表病变。所有6例患者均在全麻下于手术室行鼻内窥镜黏膜切除术。组织学检查显示为原位鳞状细胞癌(SCC)。在我们的系列中，NBI系统可能会将灵敏度提高约两倍于传统方法。结论：NBI对口咽和下咽鳞状细胞癌的诊断有重要价值。
Objectives: Narrowband imaging (NBI) is a novel optical technique that enhances the diagnostic capability of endoscopes in characterizing tissues by using narrow-bandwidth filters in a video endoscope system. The purposes of this study were to verify the effectiveness of the NBI system in conducting endoscopic screening at the oropharynx and the hypopharynx. Methods: This study was conducted between July 2005 and August 2005. During this period, 217 consecutive patients with esophageal cancer underwent endoscopic screening of the oropharynx and the hypopharynx with the NBI system at the Department of Otolaryngology, Keiyukai Sapporo Hospital. Results: Among 217 patients, 6 superficial lesions, at the oropharynx (n = 1) and at the hypopharynx (n = 5), were discovered with the NBI system. On conventional electroendoscopic view, four of six lesions could be hardly recognized because of its small diameter measuring 5 mm or less. The NBI view was more beneficial in recognizing the superficial lesions than conventional electroendoscopic view. Endoscopic mucosal resection was performed for all six patients under general anesthesia in the operation room. The histologic examination exhibited a histologically proven squamous cell carcinoma (SCC) in situ. In our series, the NBI system might improve the sensitivity by about twofold over the conventional method. Conclusion: NBI may play an important role in the diagnosis of SCCs of the oropharynx and hypopharynx.