Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6-and 12-month follow-ups
Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6-and 12-month follow-ups
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DOI：
10.1682/jrrd.2005.03.0061
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发表时间：
2005-11-01
影响因子：
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通讯作者：
Wexler, Bruce E.
中科院分区：
文献类型：
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作者：
Bell, Morris D.;Bryson, Gary J.;Wexler, Bruce E.
神经认知增强疗法（NET）包括计算机化认知训练及其他方法，已被证明可改善精神分裂症患者的工作记忆和执行功能。在本研究中，从退伍军人事务部精神卫生诊所和一个社区心理健康中心招募的145名被诊断为精神分裂症或分裂情感性障碍的门诊患者被随机分配接受6个月的有偿工作疗法（WT）或NET + WT。混合随机效应分析显示，随着时间推移，两种情况的工作小时数和所挣钱数都显著增加（p < 0.0001）。NET + WT比WT的工作小时数更多（p < 0.03），且在康复后出现差异。NET + WT的有效反应者在随访期间工作时间最长，并且往往有更多的竞争性工资就业。结果表明，NET训练提高了工作成果。对NET有反应者效果最佳。研究结果支持将认知训练纳入更广泛的康复计划时的有效性。
Neurocognitive enhancement therapy (NET), which involves computerized cognitive training and other methods, has been shown to improve working memory and executive function in schizophrenia. In the present study, 145 outpatients with diagnoses of schizophrenia or schizoaffective disorder recruited from a Department of Veterans Affairs mental hygiene clinic and from a community mental health center were randomized to 6 months of paid work therapy (WT) or to NET+WT. Mixed random effects analyses revealed significant increase in hours worked and money earned over time for both conditions (p < 0.0001). NET+WT worked more hours than WT (p < 0.03), with differences emerging after rehabilitation. Responders to NET+WT worked the most during follow-up and tended to have more competitive-wage employment. Results indicate that work outcomes were enhanced by NET training. Effects were greatest for NET responders. Findings support the efficacy of cognitive training when it is integrated into broader rehabilitation programs.