Adiposity and mortality in men

Adiposity and mortality in men
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DOI:
10.1093/aje/152.3.264
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发表时间:
2000-08-01
影响因子:
5
通讯作者:
Willett, WC
Willett, WC
中科院分区:
医学2区
文献类型:
--
作者:
Baik, I;Ascherio, A;Willett, WC

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肥胖测量与死亡率之间的关系一直是一个有争议的话题。作者对39,756名年龄在40-75岁之间的美国男性进行了前瞻性研究,研究了几种肥胖指标与总体和死因特异性死亡风险之间的关系。在10年的随访期间(1986-1996年),记录了1972例死亡(747例死于癌症,423例死于心血管疾病,802例死于其他原因)。最瘦的男性死亡风险增加的部分原因是早期随访期间的死亡率过高,以及最近有减肥史的男性死亡率高。在排除了最近体重明显减轻和在随访的头4年内死亡的男性后,老年男性的总体死亡率和心血管疾病死亡率
The relation between measures of adiposity and mortality has been a controversial topic. The authors examined prospectively the relation between several measures of adiposity and risks of overall and cause-specific mortality in 39,756 US men aged 40-75 years. During 10 years of follow-up (1986-1996), 1,972 deaths (747 from cancer, 423 from cardiovascular disease, and 802 from other causes) were documented. An elevated risk of death among the leanest men was partly accounted for by excess mortality during early follow-up and high mortality among those with a history of recent weight loss. After exclusion of men with substantial recent weight loss and deaths occurring during the first 4 years of follow-up, overall and cardiovascular disease mortality among men aged