Correlates of patterns of substance abuse among patients with schizophrenia.
Correlates of patterns of substance abuse among patients with schizophrenia.
复制标题
精神分裂症患者药物滥用模式的相关性。
DOI：
10.1176/ps.44.3.247
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Lawson,W
中科院分区：
文献类型：
--
作者：
Cuffel,BJ;Heithoff,KA;Lawson,W
以前大多数关于精神分裂症患者物质滥用的研究都没有考虑滥用物质的类型或多种物质滥用的混杂影响。作者的目标是确定一个样本的精神分裂症患者的药物滥用模式，并确定人口统计学和临床相关的这些patterns.MethodsSubjects精神分裂症被确定从流行病学集水区研究数据库，这也提供了信息滥用的物质类型和选定的人口统计学和临床特征。潜类分析被用来分组的基础上，他们的药物滥用模式的主题。Logistic回归被用来确定人口统计和临床相关的patterns.ResultsThree潜在类的基础上的物质滥用的模式被确定为：没有物质滥用，滥用酒精和大麻，和多种物质滥用。受试者的两种模式的物质滥用更有可能是年轻和男性，并有抑郁症状conclusionsThe结果不支持特定物质的滥用和特定的临床症状之间的联系，但确实表明精神分裂症患者的物质滥用和情感障碍之间的一般联系。
Most previous research on substance abuse among patients with schizophrenia has not considered the types of substances abused or the confounding influences of polysubstance abuse. The authors' goals were to identify patterns of substance abuse among a sample of subjects with schizophrenia and to determine demographic and clinical correlates of these patterns.MethodsSubjects with schizophrenia were identified from the Epidemiologic Catchment Area study data base, which also provided information on the types of substances abused and on selected demographic and clinical characteristics. Latent class analysis was used to group subjects based on their patterns of substance abuse. Logistic regression was used to identify demographic and clinical correlates of the patterns.ResultsThree latent classes based on patterns of substance abuse were identified: no substance abuse, abuse of alcohol and cannabis, and polysubstance abuse. Subjects with either of the two patterns of substance abuse were more likely to be younger and male and to have depressive symptoms.ConclusionsThe results do not support a link between abuse of specific substances and specific clinical symptoms but do suggest a general link between substance abuse and affective disturbance among schizophrenic patients.