Evidence for a dysfunction of left posterior reading areas in German dyslexic readers
Evidence for a dysfunction of left posterior reading areas in German dyslexic readers
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DOI：
10.1016/j.neuropsychologia.2006.03.010
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发表时间：
2006-01-01
期刊：
影响因子：
2.6
通讯作者：
Wimmer, Heinz
中科院分区：
文献类型：
--
作者：
Kronbichler, Martin;Hutzler, Florian;Wimmer, Heinz
对13名德国阅读困难者和15名年龄匹配的流利阅读者(年龄14~16岁)在句子阅读任务和视觉控制任务中的脑活动进行了fMRI检查。这些参与者来自一项纵向研究，阅读困难的读者从早期就表现出持续的阅读流利性缺陷。与大多数功能成像研究相一致，我们第一次在德语阅读障碍读者中发现，在左侧枕颞叶皮质和左侧边缘上回的一小部分区域，阅读障碍激活减少。左侧额叶下部和皮质下区激活增强。(C)2006爱思唯尔有限公司。保留所有权利。
The brain activity during a sentence reading task and a visual control task was examined with fMRI in 13 German dyslexic readers and 15 age-matched fluent readers (age: 14-16 years). These participants came from a longitudinal study and the dyslexic readers exhibited a persistent reading fluency deficit from early on. For the first time with German dyslexic readers, and in correspondence with the majority of functional imaging studies, we found reduced dyslexic activation in the left occipitotemporal cortex and in a small region of the left supramarginal gyrus. Enhanced activation was found in left inferior frontal and subcortical regions. (c) 2006 Elsevier Ltd. All rights reserved.