ENDOGENOUS OPIOID PEPTIDES - MULTIPLE AGONISTS AND RECEPTORS
ENDOGENOUS OPIOID PEPTIDES - MULTIPLE AGONISTS AND RECEPTORS
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DOI：
10.1038/267495a0
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发表时间：
1977-01-01
期刊：
影响因子：
64.8
通讯作者：
KOSTERLITZ, HW
中科院分区：
文献类型：
--
作者：
LORD, JAH;WATERFIELD, AA;KOSTERLITZ, HW
通过抑制脑匀浆中的3 H-纳洛酮和3 H-亮氨酸-脑啡肽结合以及抑制豚鼠回肠和小鼠输精管的收缩来测定阿片肽。阿片肽能系统具有不同特性的激动剂，与一种以上的受体相互作用。
Opioid peptides were assayed by inhibition of 3H-naloxone and 3H-leu[leucine]-enkephalin binding in brain homogenates and by depression of contractions of the guinea pig ileum and mouse vas deferens. The opioid peptidergic system had agonists of different characteristics which interacted with more than 1 type of receptor.