Surgical Management Modifications Following Systematic Additional Shaving of Cavity Margins in Breast-Conservation Treatment
Surgical Management Modifications Following Systematic Additional Shaving of Cavity Margins in Breast-Conservation Treatment
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DOI：
10.1245/s10434-010-1211-0
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发表时间：
2011-01-01
影响因子：
3.7
通讯作者：
Barranger, Emmanuel
中科院分区：
文献类型：
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作者：
Hequet, Delphine;Bricou, Alexandre;Barranger, Emmanuel
背景资料。局部广泛切除切缘阳性是局部乳腺癌复发的最重要的危险因素。当广泛的局部切除切缘为正，而空洞切缘为负时，修剪额外切缘可以降低再次切除的需要。这项从2007年1月到2008年12月的回顾性研究包括99名乳腺癌患者，她们接受了广泛的局部切除，并另外进行了4次有系统的修剪手术腔切缘。所有关于术后局部切除治疗的治疗决定都是在多学科会议上达成共识的。这种系统的口腔切除策略避免了25次再次切除(25.3%)，6名患者由于在额外的口腔切除切缘发现癌而需要重新手术，尽管局部切除切缘范围为负。术前未发现预测空洞边缘阳性的因素。系统地修剪额外的空洞边缘改变了保乳治疗后的外科处理。
Background. Positive wide local excision margins are the most important risk factor of local breast-carcinoma recurrence. Shaving additional margins could lower the need for re-excisions when wide local excision margins are positive and cavity margins are negative.Materials and Methods. This retrospective study, from January 2007 to December 2008, included 99 women with breast carcinomas who underwent wide local excision with 4 additional, systematically shaved, surgical cavity margins. All therapeutic decisions concerning post-wide local excision treatment were made by consensus during multi-disciplinary meetings.Results. This systematic cavity-shaving strategy avoided 25 re-excisions (25.3%), and 6 patients required new surgery because of carcinoma found in the additional cavity-shaving margins, despite negative wide local excision margins. No preoperative factor predictive of positive cavity margins was identified.Conclusions. Systematic shaving of additional cavity margins changed the surgical management after breast-conservation treatment.