Nickel-Catalyzed Carboxylation of Aryl and Vinyl Chlorides Employing Carbon Dioxide
Nickel-Catalyzed Carboxylation of Aryl and Vinyl Chlorides Employing Carbon Dioxide
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DOI：
10.1021/ja303514b
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发表时间：
2012-06-06
影响因子：
15
通讯作者：
Tsuji, Yasushi
中科院分区：
文献类型：
--
作者：
Fujihara, Tetsuaki;Nogi, Keisuke;Tsuji, Yasushi
本文研究了镍催化的芳基氯和氯乙烯的二氧化碳羧化反应。在镍催化剂和作为还原剂的Mn粉末的存在下，在室温下在1个大气压的CO2压力下进行反应。各种芳基氯可以以良好到高产率转化为相应的羧酸。此外，氯乙烯成功地与CO2羧化。机理研究表明，Ni（I）物种参与催化循环。
Nickel-catalyzed carboxylation of aryl and vinyl chlorides employing carbon dioxide has been developed. The reactions proceeded under a CO2 pressure of 1 atm at room temperature in the presence of nickel catalysts and Mn powder as a reducing agent. Various aryl chlorides could be converted to the corresponding carboxylic acid in good to high yields. Furthermore, vinyl chlorides were successfully carboxylated with CO2. Mechanistic study suggests that Ni(I) species is involved in the catalytic cycle.