Myocardial fibrosis: why image, how to image and clinical implications
Myocardial fibrosis: why image, how to image and clinical implications
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DOI：
10.1136/heartjnl-2019-315560
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发表时间：
2019-12-01
期刊：
影响因子：
5.7
通讯作者：
Dweck, Marc Richard
中科院分区：
文献类型：
--
作者：
Bing, Rong;Dweck, Marc Richard
当前时代心肌成像技术取得了重大进展。我们现在能够评估各种疾病状态下的心脏解剖结构、功能、组织成分和疾病活动性。最近，人们对心肌纤维化成像（主要是心血管磁共振（CMR））产生了浓厚的兴趣。纤维化代表了大多数心肌病对损伤的常见反应，但纤维化的分布和模式因病理而异，强调了其作为诊断标志物的潜在作用。此外，纤维化与左心室功能受损以及心律失常密切相关。因此，纤维化成像还提供了强大的预后信息。
The current era has seen major advances in myocardial imaging. We are now able to assess cardiac anatomy, function, tissue composition and disease activity across a wide range of disease states. Recently, there has been major interest in imaging myocardial fibrosis, predominantly with cardiovascular magnetic resonance (CMR). Fibrosis represents a common response to injury in most cardiomyopathies, but the distribution and pattern of fibrosis differ between pathologies, underscoring its potential role as a diagnostic marker. Furthermore, fibrosis is closely associated with impaired left ventricular function, as well as cardiac arrhythmias; as such, fibrosis imaging also provides powerful prognostic information.