BEHAVIORAL-CORRELATES OF VITAMIN-D DEFICIENCY
BEHAVIORAL-CORRELATES OF VITAMIN-D DEFICIENCY
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DOI：
10.1016/0031-9384(87)90369-6
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发表时间：
1987-01-01
影响因子：
2.9
通讯作者：
BIRGE, SJ
中科院分区：
文献类型：
--
作者：
ALTEMUS, KL;FINGER, S;BIRGE, SJ
为了验证维生素D缺乏改变行为和学习的假说，在断奶时缺乏维生素D的大鼠与对照组大鼠进行了旷场、稳定器、放射臂迷宫和空间颠倒任务的比较。与对照组相比，缺陷大鼠的野外饲养活动更少，每天在放射状迷宫中花费的时间更多。这些发现与维生素D对肌肉骨骼系统的已知影响是一致的。剥夺组大鼠的学习成绩与对照组无显著差异。这将表明维生素D缺乏可能不会显著损害年轻成年大鼠的认知功能。
Rats deprived of vitamin D at weaning were compared to control rats on open field, stabilimeter, radial arm maze and spatial reversal tasks in order to test the hypothesis that vitamin D deficiency alters behavior and learning. The deficient animals engaged in statistically less open field rearing activity and spent more time each day negotiating the radial maze than did the control rats. These findings are consistent with the known influence of vitamin D on the musculoskeletal system. The deprived rats did not differ from the control animals on the learning measures. This would indicate that vitamin D deficiency may not significantly impair cognitive functions in young adult rats.