Synthesis of 5-Phenyl 2-Functionalized Pyrroles by Amino Heck and Tandem Amino Heck Carbonylation Reactions
Synthesis of 5-Phenyl 2-Functionalized Pyrroles by Amino Heck and Tandem Amino Heck Carbonylation Reactions
复制标题
DOI：
10.1071/ch07132
复制
发表时间：
2007-08
影响因子：
1.1
通讯作者：
S. Zaman;Mitsuru Kitamura;A. Abell
中科院分区：
文献类型：
--
作者：
S. Zaman;Mitsuru Kitamura;A. Abell
以相应的3-丁炔基和4-甲氧羰基-3-丁炔基苯基酮O-五氟苯甲酰基肟为原料，分别经氨基Heck环化和串联氨基Heck羰基化反应，合成了2-甲基、2-甲氧羰基甲基和2，2-乙氧羰基（甲氧羰基）甲基-5-苯基吡咯。
2-Methyl-, 2-(methoxycarbonyl)methyl-, and 2,2-[(ethoxycarbonyl)(methoxycarbonyl)]methyl-5-phenylpyrroles are prepared from the corresponding 3-butynyl and 4-(methoxycarbonyl)-3-butynyl phenyl ketone O-pentafluorobenzoyl oximes by amino Heck cyclization and tandem amino Heck carbonylation, respectively.