DEVELOPMENT OF ACETYLCHOLINE RECEPTOR CLUSTERS ON CULTURED MUSCLE-CELLS
DEVELOPMENT OF ACETYLCHOLINE RECEPTOR CLUSTERS ON CULTURED MUSCLE-CELLS
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DOI：
10.1073/pnas.70.1.270
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发表时间：
1973-01-01
影响因子：
11.1
通讯作者：
NIRENBERG, MW
中科院分区：
文献类型：
--
作者：
SYTKOWSKI, AJ;VOGEL, Z;NIRENBERG, MW
在培养的鸡胚骨骼肌细胞的发育过程中，在没有神经元的情况下形成了乙酰胆碱受体簇。簇中受体的平均浓度估计为每μm2 9000 个。在细胞的其他区域，受体浓度为 900 个/μm2。提出了受体簇可能参与突触形成的可能性。
Clusters of acetylcholine receptors were formed in the absence of neurons during the development of cultured chick-embryo skeletal muscle cells. The average concentration of receptors in clusters was estimated to be 9000 per μm2. At other regions of the cell, receptor concentration was 900 per μm2. The possibility that receptor clusters may participate in synapse formation is suggested.