Skull Expansion in Experimental Craniosynostosis
Skull Expansion in Experimental Craniosynostosis
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实验性颅缝早闭中的颅骨扩张
DOI：
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发表时间：
1986
影响因子：
3.6
通讯作者：
John A. Per sing
中科院分区：
文献类型：
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作者：
J. Persing;W. Babler;M. Nagorsky;M. Edgerton;J. Jane;John A. Per sing
采用双侧冠状面缝合固定9日龄家兔，模拟冠状面缝闭特征的短头畸形。生长异常由连续x线测量记录。在60日龄用固定冠状缝线对家兔进行“矫正”直线颅骨切除术。将这些动物的手术诱导异常的改善程度与在冠状缝合颅骨切除术部位进行相同手术并补充植入弹簧膨胀装置的类似动物组进行比较。弹簧扩张器植入后冠状缝合线处的平均标记物分离明显大于单纯直线颅骨切除术（5.61 mm±0.52 SE vs 2.53 mm±0.38 SE; p < 0.05）。同样，通过额外使用弹簧膨胀装置，诱发的前颅底缩短和颅面测头仪畸变也得到了更显著的改善。
Bilateral coronal suture immobilization was performed in 9‐day‐old rabbits to simulate the brachycephaly deformity characteristic of coronal synostosis. Growth abnormalities were documented by serial radiographic cephalometry. A “corrective” linear craniectomy procedure was performed on the rabbits with an immobilized coronal suture at 60 days of age. The degree of amelioration of the induced abnormalities by the surgery in these animals was compared with a similar group of animals that had the same surgery plus supplemental implantation of a spring expansion device at the coronal suture craniectomy site. The mean marker separation at the coronal suture was significantly greater (5.61 mm ± 0.52 SE versus 2.53 mm ± 0.38 SE; p < 0.05) following spring expander implantation than with linear craniectomy alone. Similarly, induced anterior cranial base shortening and distortion of craniofacial cephalometrics were more significantly improved by the additional use of the spring expansion device.