Surging Hormones: Brain-Behavior Interactions During Puberty.
Surging Hormones: Brain-Behavior Interactions During Puberty.
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激素激增：青春期期间的脑行为相互作用。
DOI：
10.1177/0963721412473755
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发表时间：
2013-04
影响因子：
7.2
通讯作者：
Dahl RE
中科院分区：
文献类型：
--
作者：
Peper JS;Dahl RE
在本文中，我们讨论了青春期激素的激增及其对青少年行为的影响。我们描述了为什么这些问题是一个有趣和重要的研究领域，强调它们对一套特定的发展过程的贡献，这些发展过程是从儿童到青少年过渡的核心。我们简要回顾了人类青春期的神经内分泌基础。我们的综述集中于性腺激素对行为(和神经行为)影响的证据，并强调这些激素影响的社会和情感维度。更广泛地说，我们考虑了这些荷尔蒙事件对大脑-行为相互作用的影响，这些相互作用可能会使青春期早期的轨迹朝着积极和消极的方向偏向，而且一开始可能是微小的影响，但随着时间的推移可能会螺旋式上升为大规模影响。这些影响似乎也在青春期大脑的功能和结构发育中发挥着重要作用。最后，我们对这些领域未来的研究方向提出了一些思考。
In this paper we discuss the surging hormones of puberty and their influences on adolescent behavior. We describe why these issues represent an interesting and important area of investigation, emphasizing their contributions to a specific set of developmental processes at the heart of the transition from childhood to adolescence. We briefly review the neuroendocrine underpinnings of human puberty. Our review focuses on evidence for behavioral (and neurobehavioral) effects of gonadal hormones, and emphasizes the social and affective dimensions of these hormonal effects. More broadly, we consider how these hormonal events contribute to brain-behavior interactions that can bias early adolescent trajectories in both positive and negative directions, and in ways that may begin as small influences, but can spiral into large-scale effects over time. These influences also appear to play an important role in functional and structural brain development during adolescence. Finally we offer some thoughts on directions for future research in these areas.