Combined heart rate variability and pulse oximetry biofeedback for chronic obstructive pulmonary disease: Preliminary findings
Combined heart rate variability and pulse oximetry biofeedback for chronic obstructive pulmonary disease: Preliminary findings
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DOI：
10.1023/b:apbi.0000026638.64386.89
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发表时间：
2004-06-01
影响因子：
3
通讯作者：
Borson, S
中科院分区：
文献类型：
--
作者：
Giardino, ND;Chan, L;Borson, S
本研究的目的是研究包括心率变异性（HRV）生物反馈和脉搏血氧测量反馈在内的干预措施的可行性，以改善慢性阻塞性肺疾病（COPD）患者的功能和生活质量。20例COPD患者参加了每周5次HRV生物反馈和每周4次血氧反馈步行练习，并指导每日在家练习。主要结果测量是6分钟步行距离（6MWD）和总体生活质量，由圣乔治呼吸问卷（SGRQ）测量。次要结局包括自我效能、自我报告的残疾、焦虑、抑郁、6MWD前后的呼吸困难，以及自主呼吸和有节奏呼吸时呼吸频率的HRV。经过10周的训练，参与者在6MWD和生活质量方面表现出统计学和临床意义上的显著改善。6MWD前后的自我效能感、残疾、呼吸困难、自主呼吸时HRV振幅也有显著变化。我们的结论是，我们的干预措施对COPD患者是可行的，进一步的随机对照研究是有必要的。
The purpose of this study was to examine the feasibility of an intervention that included heart rate variability (HRV) biofeedback and walking with pulse oximetry feedback to improve functioning and quality of life for patients with chronic obstructive pulmonary disease ( COPD). Twenty patients with COPD participated in 5 weekly sessions of HRV biofeedback and 4 weekly sessions of walking practice with oximetry feedback, with instructions for daily home practice. Primary outcomes measures were the distance walked in 6 min (6MWD) and overall quality of life, as measured by the St. George's Respiratory Questionnaire (SGRQ). Secondary outcomes included measures of self-efficacy, self-reported disability, anxiety, depression, dyspnea before and after the 6MWD, and HRV at the frequency of respiration during spontaneous and paced breathing. After 10 weeks of training, participants showed statistically and clinically significant improvements in 6MWD and quality of life. Significant changes were also seen in self-efficacy, disability, dyspnea before and after the 6MWD, and HRV amplitude during spontaneous breathing. We conclude that our intervention is feasible for patients with COPD and that further research using a randomized controlled design is warranted.