Mentalizing in Female Inpatients With Major Depressive Disorder
Mentalizing in Female Inpatients With Major Depressive Disorder
复制标题
DOI：
10.1097/nmd.0b013e3182845c0a
复制
发表时间：
2013-03-01
影响因子：
1.9
通讯作者：
Leithner, Katharina
中科院分区：
文献类型：
--
作者：
Fischer-Kern, Melitta;Fonagy, Peter;Leithner, Katharina
抑郁症与社会和人际功能的严重损害有关。然而，很少有研究涉及可能导致这些损伤的心智能力缺陷。因此，本研究的目的是调查女性抑郁症住院患者的心智化能力，并与健康对照进行比较。我们评估了46例重度抑郁症住院患者的精神诊断、抑郁严重程度、认知障碍和语言智力。此外，还包括20名性别、年龄和教育程度相匹配的健康对照者。在成人依恋访谈中使用反思功能量表对心智化进行评分。女性抑郁症住院患者的心理化能力明显低于健康对照组。心智缺陷并不局限于抑郁症特有的话题。此外，心智能力的缺陷与病程、入院次数和认知障碍有关。结果表明，女性抑郁症住院患者对自我和他人心理状态的识别和解释能力严重受损。与疾病持续时间和入院人数的相关性表明，慢性抑郁症会导致进一步的精神障碍。对心理化的调查可能对开发针对抑郁症的有针对性的心理治疗干预措施特别重要。
Depression is associated with profound impairments in social and interpersonal functioning. However, little research has addressed deficits in mentalizing capacity that may underlie these impairments. The aim of this study was, therefore, to investigate the capacity for mentalization in female inpatients with depression in comparison with healthy controls. We assessed 46 inpatients with major depressive disorder with regard to psychiatric diagnoses, severity of depression, cognitive impairment, and verbal intelligence. In addition, 20 healthy controls matched for sex, age, and education were included. Mentalization was scored on the Adult Attachment Interview using the Reflective Functioning Scale. The female inpatients with depression showed a significantly lower capacity for mentalization compared with the healthy controls. Mentalization deficits were not restricted to depression-specific topics. Moreover, deficits in mentalizing capacity were related to illness duration, number of admissions, and cognitive impairment. The results indicate severe impairment in the ability of the female inpatients with depression to identify and interpret mental states of the self and others. Correlations with illness duration and number of admissions suggest that a chronic course of depression results in further mentalizing impairments. The investigation of mentalization may be of particular importance for the development of targeted psychotherapeutic interventions for depression.