IUPAC RECOMMENDATIONS FOR THE REPRESENTATION OF REACTION-MECHANISMS
IUPAC RECOMMENDATIONS FOR THE REPRESENTATION OF REACTION-MECHANISMS
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DOI：
10.1021/ar00166a001
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发表时间：
1989-10-01
影响因子：
18.3
通讯作者：
JENCKS, WP
中科院分区：
文献类型：
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作者：
GUTHRIE, RD;JENCKS, WP
大约10年前，IUPAC物理有机化学委员会开始着手为反应机制的命名制定一套建议。最初，对于是否应修订英戈尔德2设计的行之有效的制度或建议采取新的办法，各方进行了激烈的讨论。随后，一个工作小组进行了艰苦的努力，致力于保留经修订的英戈德式系统，但尽管经过大约两年的讨论，委员会还是决定，修改英戈德式系统是不切实际的。InGold命名系统被设计用来描述观察到的有机反应的性质：双分子亲核取代是SN2反应。这个词并不是用来描述反应机制的，尽管这个词甚至在英戈尔德本人也被广泛地用来描述反应机制。英戈尔德编码说明了转变的类型和观察到的分子--
About 10 years ago, theIUPAC Commission on Physical Organic Chemistry set about the task of pro-ducing a set of recommendations for the naming of reaction mechanisms. Initially there was vigorous de-bate as to whether the well-established system designed by Ingold2 should be revised or a new approach recom-mended. There followed an arduous effort by a working party dedicated to the retention of a revised Ingold-type system, but despite discussion over a period of about two years, the commission decided that revision of the Ingold system was impractical. The Ingold system of nomenclature was designed to describe the observed properties of an organic reaction: A bimolecular nucleophilic substitution is an SN2 re-action. It was not designed to describe reaction mech-anisms, although it has been widely used for that pur-pose even by Ingold himself. The Ingold code states the type of transformation and the observed molecu-