Release of Metaraminol (Aramine) from the Heart by Sympathetic Nerve Stimulation
Release of Metaraminol (Aramine) from the Heart by Sympathetic Nerve Stimulation
复制标题
通过交感神经刺激从心脏释放间羟胺（Aramine）
作者：
J. Crout;H. Alpers;E. Tatum;P. A. Shore
猫被静脉注射间羟胺，一种从交感神经末梢消耗去甲肾上腺素的胺，然后在体外灌注它们的心脏。刺激交感神经供应从心脏释放间羟胺，表明合成化合物可以取代去甲肾上腺素，并作为肾上腺素能神经末梢的递质
Cats were injected intravenously with metaraminol, an amine which depletes norepinephrine from the sympathetic nerve endings; their hearts were then perfused in vitro. Stimulation of the sympathetic nerve supply released metaraminol from the hearts, demonstrating that a synthetic compound can replace norepinephrine and serve as a transmitter at adrenergic nerve endings