The impact of pregnancy induced hypertension on low birth weight in Ethiopia: systematic review and meta-analysis.
The impact of pregnancy induced hypertension on low birth weight in Ethiopia: systematic review and meta-analysis.
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DOI：
10.1186/s13052-020-00926-0
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发表时间：
2020-11-26
影响因子：
3.6
通讯作者：
Desta M
中科院分区：
文献类型：
--
作者：
Getaneh T;Negesse A;Dessie G;Desta M
尽管降低新生儿死亡率是到2030年需要实现的主要目标，但这一数字仍然高得令人无法接受，特别是在埃塞俄比亚。另一方面，出生体重不足是新生儿死亡和发病的主要原因。超过1000万的低出生体重婴儿是由于妊娠高血压引起的。然而，在埃塞俄比亚，低出生体重和妊娠高血压之间的关联是由未更新的、不确定的和不同的研究代表的。因此，本综述旨在评估妊娠高血压综合征对埃塞俄比亚低出生体重儿的总体影响及其相关性。在PubMed/Medline、EMBASE、CINAHL、科克伦图书馆、Google、Google Scholar和当地书架上检索的文章。应用Joanna Briggs Institute统计评估和审查工具的荟萃分析（JBI-MAStARI）进行关键评价。计算I2统计量以检查异质性的存在。采用漏斗图不对称性和Egger检验评价发表偏倚。采用随机效应模型估计低出生体重的合并患病率。在识别出的131篇原始文献中，25篇合格并纳入最终分析。埃塞俄比亚妊娠高血压妇女中低出生体重的总体合并患病率为39.7%（95% CI：33.3，46.2）。但是，I2统计估计证明了纳入研究之间的显著异质性（I2 = 89.4，p < 0.001）。此外，妊娠高血压综合征患者的低出生体重儿的几率是其对应人群的3.89倍（OR = 3.89，95%CI：2.66，5.69）。患有妊娠高血压综合征的妇女中低出生体重的合并患病率比所有育龄妇女中低出生体重的合并估计值高两倍以上。与血压正常的妇女相比，患有妊娠高血压综合征的妇女发生低出生体重的几率也增加了近四倍。因此，卫生政策，提供更好的和高质量的产前保健，更注重早期发现和管理妊娠高血压综合征的重要性，应实施。
Even though neonatal mortality reduction is the major goal needed to be achieved by 2030, it is still unacceptably high especially in Ethiopia. In the other hand, low birth weight is the major cause of neonatal mortality and morbidity. More than 10 millions of low birth weight infants occurred as a result of pregnancy induced hypertension. However, in Ethiopia the association between low birth weight and pregnancy induced hypertension was represented with un-updated, inconclusive and different studies. Therefore, this review aimed to estimate the overall pooled impact of pregnancy induced hypertension on low birth weight and its association in Ethiopia. articles searched on PubMed/Medline, EMBASE, CINAHL, Cochrane library, Google, Google Scholar and local shelves. Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was applied for critical appraisal. The I2 statistic was computed to check the presence of heterogeneity. Publication bias was evaluated using funnel plot asymmetry and Egger’s test. A random effect model was used to estimate the pooled prevalence of low birth weight. From the total 131 identified original articles, 25 were eligible and included for the final analysis. The overall pooled prevalence of low birth weight among women who had pregnancy induced hypertension in Ethiopia was 39.7% (95% CI: 33.3, 46.2). But, I2 statistic estimation evidenced significant heterogeneity across included studies (I2 = 89.4, p < 0.001). In addition, the odds of having low birth weight newborns among women who had pregnancy induced hypertension was 3.89 times higher compared to their counterparts (OR = 3.89, 95% CI: 2.66, 5.69). The pooled prevalence of low birth weight among women who had pregnancy induced hypertension was more than two times higher than the pooled estimate of low birth weight among all reproductive aged women. The odds of low birth weight also increased nearly four times among women with pregnancy induced hypertension than normotensive women. Therefore, health policies which provide better and quality antenatal care with more oriented on importance of early detection and management of pregnancy induced hypertension should be implemented.
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影响因子：
9.8
作者：
Bramham, Kate;Briley, Annette L.;Chappell, Lucy C.
通讯作者：
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影响因子：
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作者：
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DOI：
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发表时间：
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影响因子：
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