Vaccination of solid organ transplant candidates and recipients: Guidelines from the American society of transplantation infectious diseases community of practice
Vaccination of solid organ transplant candidates and recipients: Guidelines from the American society of transplantation infectious diseases community of practice
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DOI：
10.1111/ctr.13563
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发表时间：
2019-09-01
影响因子：
2.1
通讯作者：
Kumar, Deepali
中科院分区：
文献类型：
--
作者：
Danziger-Isakov, Lara;Kumar, Deepali
AST IDCOP的这些更新指南回顾了实体器官移植候选者和接受者的疫苗接种。讨论了接种疫苗的一般原则以及在这一人群中使用特定疫苗的情况。应在移植前环境中审查疫苗接种情况，并更新适当的疫苗。灭活疫苗和活疫苗都可以在移植前接种。应考虑移植后接种疫苗的时间。在移植后的情况下，灭活疫苗可以在移植后3个月开始接种，但流感除外，最早可以在一个月内接种。灭活疫苗可以在移植后安全地接种。有越来越多的数据表明，也可以为选定的移植后患者接种减毒活疫苗。移植患者的密切接触者可以接种大多数常规活疫苗。具体的疫苗包括肺炎、流感、乙肝、人乳头瘤病毒和脑膜炎双球菌疫苗进行了讨论。重点介绍了季节性流感疫苗和带状疱疹的较新疫苗。还讨论了麻疹、腮腺炎、风疹和水痘等减毒活疫苗。重点介绍了有关移植后减毒活疫苗的新数据。
These updated guidelines of the AST IDCOP review vaccination of solid organ transplant candidates and recipients. General principles of vaccination as well as the use of specific vaccines in this population are discussed. Vaccination should be reviewed in the pre-transplant setting and appropriate vaccines updated. Both inactivated and live vaccines can be given pre-transplant. The timing of vaccination post-transplant should be taken into account. In the post-transplant setting, inactivated vaccines can be administered starting at 3 months post-transplant with the exception of influenza which can be given as early as one month. Inactivated vaccines can be safely administered post-transplant. There is accumulating data that live-attenuated vaccines can also be given to select post-transplant patients. Close contacts of transplant patients can receive most routine live vaccines. Specific vaccines including pneumococcal, influenza, hepatitis B, HPV, and meningococcal vaccines are discussed. Newer vaccines for seasonal influenza vaccine and herpes zoster are highlighted. Live-attenuated vaccines such as measles, mumps, rubella, and varicella are also discussed. Emerging data on live-attenuated vaccines post-transplant are highlighted.