Waist Circumference, Body Mass Index, and Other Measures of Adiposity in Predicting Cardiovascular Disease Risk Factors among Peruvian Adults.
Waist Circumference, Body Mass Index, and Other Measures of Adiposity in Predicting Cardiovascular Disease Risk Factors among Peruvian Adults.
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DOI：
10.4061/2011/931402
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发表时间：
2011-01-24
影响因子：
1.9
通讯作者：
Williams MA
中科院分区：
文献类型：
--
作者：
Knowles KM;Paiva LL;Sanchez SE;Revilla L;Lopez T;Yasuda MB;Yanez ND;Gelaye B;Williams MA
目标.研究肥胖指标在何种程度上可用于预测代谢综合征（MetS）和C反应蛋白（CRP）升高的选定组分。方法.共有1，518名秘鲁成年人参与了这项研究。测量腰围（WC）、体重指数（BMI）、腰臀比（WHR）、腰高比（WHtR）和内脏脂肪指数（VAI）。根据每个人体测量的三分位数确定每个MetS组分的患病率。ROC曲线被用来评估肥胖的测量可以预测心血管风险的程度。结果肥胖的所有措施有最强的相关性与甘油三酯浓度（TG）。对于两种性别，随着肥胖的增加，Mets组分的患病率增加。与低BMI和低WC的个体相比，高BMI和高WC的男性和女性有更高的空腹血糖、血压、TG升高和HDL降低的几率，而只有这一类男性有更高的CRP升高几率。总体而言，ROC显示VAI、WC和WHtR是单个MetS组分的最佳预测因子。结论.我们的研究结果表明，肥胖的措施与心血管疾病的风险，虽然没有一个单一的肥胖措施被确定为最好的预测代谢综合征。
Objectives. To examine the extent to which measures of adiposity can be used to predict selected components of metabolic syndrome (MetS) and elevated C-reactive protein (CRP). Methods. A total of 1,518 Peruvian adults were included in this study. Waist circumference (WC), body mass index (BMI), waist-hip ratio (WHR), waist-height ratio (WHtR), and visceral adiposity index (VAI) were examined. The prevalence of each MetS component was determined according to tertiles of each anthropometric measure. ROC curves were used to evaluate the extent to which measures of adiposity can predict cardiovascular risk. Results. All measures of adiposity had the strongest correlation with triglyceride concentrations (TG). For both genders, as adiposity increased, the prevalence of Mets components increased. Compared to individuals with low-BMI and low-WC, men and women with high-BMI and high- WC had higher odds of elevated fasting glucose, blood pressure, TG, and reduced HDL, while only men in this category had higher odds of elevated CRP. Overall, the ROCs showed VAI, WC, and WHtR to be the best predictors for individual MetS components. Conclusions. The results of our study showed that measures of adiposity are correlated with cardiovascular risk although no single adiposity measure was identified as the best predictor for MetS.