Body composition and hip fracture type in elderly women

Body composition and hip fracture type in elderly women
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DOI:
10.1007/s10067-003-0750-1
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发表时间:
2004-02-01
影响因子:
3.4
通讯作者:
Cavanna, A
Cavanna, A
中科院分区:
医学3区
文献类型:
--
作者:
Di Monaco, M;Vallero, F;Cavanna, A

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许多观察结果支持这一观点,即股骨转子骨折患者与股骨颈骨折患者之间存在显著差异。我们的目的是评估软组织成分(脂肪和瘦肉间室)和髋部骨折类型之间的关系。在120名第一次髋骨骨折的连续女性中,102名被纳入了这项横断面研究。DXA评估身体成分。粗隆骨折女性的体脂量低于颈椎骨折女性(组间差异:2.86 kg; 95% CI 0.10-5.61 kg; p=0.042)。脂肪百分比为30.75+/-8.77(平均值+/-SD)vs 34.75+/-7.29(组间差异:4.00; 95% CI 0.84-7.16; p=0.014)。相比之下,两组之间的瘦体重没有显着差异。Logistic多元回归分析显示,脂肪量与骨折类型相关,与年龄、身高、体重、骨折发生与DEXA评估之间的时间、合并症、药物使用数量、瘦体重和骨矿物质含量无关。当脂肪百分比替代脂肪质量时,logistic回归结果相似。数据显示,肥胖而非瘦体重与髋部骨折类型相关,有助于定义颈椎或转子骨折患者之间的差异。我们强调,在进行与身体成分有关的临床或流行病学研究时,包括营养或体育锻炼方面的研究时,必须区分这两种类型的骨折。
Many observations support the view that there are significant differences between patients sustaining trochanteric fractures and those sustaining cervical fractures of the hip. Our aim was to evaluate the association between soft tissue composition (fat and lean compartments) and the type of hip fracture sustained. Of 120 consecutive women affected by their first hip fracture admitted to our rehabilitation hospital 102 were included in this cross-sectional study. Body composition was assessed by DXA. Body fat mass was lower in the women with trochanteric fracture than in those with cervical fracture (difference between groups: 2.86 kg; 95% CI 0.10-5.61 kg; p=0.042). The percentage of fat was 30.75+/-8.77 (mean+/-SD) versus 34.75+/-7.29 (difference between groups: 4.00; 95% CI 0.84-7.16; p=0.014). In contrast, no meaningful differences in body lean mass were shown between the two groups. Logistic multiple regression showed that fat mass was associated with the type of fracture independently of age, height, weight, time between fracture occurrence and DEXA assessment, comorbidity, number of drugs in use, lean mass and bone mineral content. The logistic regression results were similar when fat percentage was substituted for fat mass. The data show that fat but not lean body mass is associated with the type of hip fracture, contributing to the definition of the differences between patients sustaining cervical or trochanteric fractures. We stress the importance of distinguishing the two types of fracture when clinical or epidemiological studies related to body composition, including those regarding nutrition or physical exercise, are performed.