Surgical ventricular restoration to reverse left ventricular remodeling.
Surgical ventricular restoration to reverse left ventricular remodeling.
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DOI：
10.2174/157340310790231626
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发表时间：
2010-02
影响因子：
1.9
通讯作者：
Donato MD
中科院分区：
文献类型：
--
作者：
Castelvecchio S;Menicanti L;Donato MD
心力衰竭是西方世界的主要卫生保健问题之一。越来越多的病人受到影响，导致住院率高和费用高。即使给予现有的最佳治疗，死亡率仍然很高。心肌梗死后左心室容积的增加是重构过程的一个组成部分。外科心室修复术（SVR）已被引入作为一种可选的治疗策略，以减少左心室容量和恢复心脏几何形状。到目前为止，已经确定SVR可以改善缺血性、扩张型心肌病和心力衰竭患者的心功能、临床状态和生存率。自第一次描述以来，SVR一直在努力使程序标准化并优化结果。本综述将讨论手术逆转左心室重构的基本原理、SVR技术、其对心功能和生存率的影响以及未来的展望。
Heart failure is one of the major health care issues in the Western world. An increasing number of patients are affected, leading to a high rate of hospitalization and high costs. Even with administration of the best available medical treatment, mortality remains high. The increase in left ventricular volume after a myocardial infarction is a component of the remodeling process. Surgical Ventricular Restoration (SVR) has been introduced as an optional therapeutic strategy to reduce left ventricular volume and restore heart geometry. So far, it has been established that SVR improves cardiac function, clinical status, and survival in patients with ischemic, dilated cardiomyopathy and heart failure. Since its first description , SVR has been refined in an effort to standardize the procedure and to optimize the results. This review will discuss the rationale behind surgical reversal of LV remodeling, the SVR technique, its impact on cardiac function and survival, and future expectations.