The scientific career and life of Edmond H. Fischer-A personal tribute.
The scientific career and life of Edmond H. Fischer-A personal tribute.
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埃德蒙·H·费舍尔的科学事业和一生——个人致敬。
作者：
Cohen P
我很高兴被邀请为《IUBMB Life on Protein Phosphorylation》特刊撰写介绍性文章，献给埃德蒙·亨利·费舍尔（Edmond Henri Fischer），他的所有朋友都简称他为Eddy，他于2021年8月27日去世，享年101岁。埃迪是一位伟大的科学家，对音乐、历史和艺术充满热情。他有一个令人兴奋、多事和充实的生活，但他也是一个善良和慷慨的人。从1969年到1971年，我在他的实验室里度过了两年，这两年是我一生中最重要的时期之一，如果我没有遇到他并与他一起工作，我的职业生涯和生活将会完全不同。自埃迪去世以来，已经出现了一些关于他的讣告，所以只会简要地提到他的早年生活。读者可以参考另一篇文章，详细介绍他的早期生活和成长经历。1简而言之，Eddy于1920年出生于中国上海。他的家人搬到瑞士时，他是7和他接受教育附近的日内瓦，高中毕业于1939年。随后，他在日内瓦大学学习化学和生物学，在那里他获得了有机化学理学学士学位，然后在1947年获得博士学位，在Kurt Meyer的指导下研究多糖和α-淀粉酶的结构。埃迪搬到美国在1953年开始博士后研究在加州理工学院，但抵达意外提供了一个助理教授在生物化学在华盛顿大学，西雅图，他接受了，度过余生。
I am delighted to have been invited to write the introductory article of this special issue of IUBMB Life on Protein Phosphorylation dedicated to Edmond Henri Fischer, known simply as Eddy to all his friends, who died on 27 August 2021, at the age of 101. Eddy was a great scientist with a passion for music, history and art. He had an exciting, eventful and fulfilling life, but he was also a kind and generous person. The 2 years I spent in his laboratory from 1969 to 1971 were among the most formative of my life, and my career and life would have been entirely different had I not met and worked with him. A number of obituaries about Eddy have appeared since his death, and so will only mention his early life briefly. Readers are referred to another article for a detailed account of his early life and upbringing. 1 Briefly, Eddy was born in Shanghai, China in 1920. His family moved to Switzerland when he was seven and he was educated near Geneva, graduating from high school in 1939. He then studied chemistry and biology at the University of Geneva, from where he received a Bachelor of Science degree in Organic Chemistry and then a PhD in 1947 for research on the structure of polysaccharides and alphaamylases under the supervision of Kurt Meyer. Eddy moved to the USA in 1953 to begin postdoctoral research at Caltech but on arrival was unexpectedly offered an assistant professorship in biochemistry at the University of Washington, Seattle, which he accepted, spending the rest of his life there.