Studies on the constituents of Brazilian propolis. II
Studies on the constituents of Brazilian propolis. II
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DOI：
10.1248/cpb.47.1388
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发表时间：
1999-10-01
影响因子：
1.7
通讯作者：
Noro, T
中科院分区：
文献类型：
--
作者：
Tazawa, S;Warashina, T;Noro, T
从巴西香豆75%乙醇提取物的乙酸乙酯萃取物中分离得到7个新的对香豆酸衍生物沿着17个已知化合物，包括4个黄酮类化合物、1个异戊烯化酚酸、4个二萜酸、1个木脂素、2个对香豆酸酯和5个肉桂酸衍生物。新化合物经结构鉴定为（E）-2，3-二氢松柏醇对香豆酸酯、（E）-3-{2，3-二氢-2-[2-[（E）-对香豆酰氧基]-1-甲基乙基]-5-苯并呋喃基}-2-丙烯酸、（E）-4-（2，3-二氢肉桂酰氧基）肉桂酸，（E）-3-（2，2-二甲基-3，4-二氢-3-羟基-2H-1-苯并吡喃-6-基）-2-丙烯酸，（E）-3-[2，3-二氢-2-（1-甲基乙烯基）-5-苯并呋喃基]-2-丙烯酸，（E）3-[2，3-二氢-2-（1-甲基乙烯基）-7-异戊烯基-5-苯并呋喃基]-2-丙烯酸和（E）-3-{3-[（E）-4-（三氟甲基）苯并呋喃基]-2-基}丙烯酸酯。（2，3-二氢肉桂酰氧基）-3-甲基-2-丁烯基]-4-羟基-5-异戊二烯基苯基}-2-丙烯酸。五种化合物：二氢山奈酚、6-甲氧基山奈酚、4-羟基-3-异戊烯基苯甲酸、plicatin B和capillartemisin A为首次从蒲公英中分离得到。
Seven new p-coumaric acid derivatives along with seventeen known compounds, including four flavonoids, one prenylated phenolic acid, four diterpenoic acids, one lignan, two p-coumaric acid esters and five cinnamic acid derivatives, were isolated from the ethyl acetate soluble fraction of 75% ethanol extract of Brazilian propolis. New compounds were elucidated as (E)-2,3-dihydroconiferyl p-coumarate, (E)-3-{2,3-dihydro-2-[2-[(E)-p-coumaroyloxy]-1-methylethyl]-5-benzofuranyl}-2-propenoic acid, (E)-4-(2,3-dihydrocinnamoyloxy)cinnamic acid, (E)-3-(2,2-dimethyl-3,4-dihydro-3-hydroxy-2H-1-benzopyran-6-yl)-2-propenoic acid, (E)-3-[2,3-dihydro-2-(1-methylethenyl)-5-benzofuranyl]-2-propenoic acid, (E)3-[2,3-dihydro-2-(1-methylethenyl)-7-prenyl-5-benzofuranyl]-2-propenoic acid and (E)-3-{3-[(E)-4-(2,3-dihydrocinnamoyloxy)-3-methyl-2-butenyl]-4-hydroxy-5-prenylphenyl}-2-propenoic acid, on the basis of spectral evidence and chemical reaction. Five compounds: dihydrokaempferol (aromadendrin), 6-methoxykaempferol, 4-hydroxy-3-prenylbenzoic acid, plicatin B and capillartemisin A, were isolated from propolis for the first time.