Shining a light on posterior cortical atrophy

Shining a light on posterior cortical atrophy
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DOI:
10.1016/j.jalz.2012.11.004
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发表时间:
2013-07-01
影响因子:
14
通讯作者:
Fox, Nick C.
Fox, Nick C.
中科院分区:
医学1区
文献类型:
--
作者:
Crutch, Sebastian J.;Schott, Jonathan M.;Fox, Nick C.

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后皮质萎缩(PCA)是一种临床放射学综合征,其特征是视觉处理技能进行性下降,早期记忆和语言相对完整,以及后部脑区域萎缩。PCA的误诊是常见的,这不仅是因为它相对罕见,不寻常和可变的表现,而且还因为患者经常首先寻求眼科医生的意见,他们可能会注意到正常的眼科检查,但可能不会意识到大脑皮质功能障碍。为了提高人们对这种疾病的认识,刺激研究,促进合作,一个多学科的PCA研究临床医生小组成立了一个国际工作组,该工作组于2012年7月13日在加拿大温哥华举行了第一次面对面的会议,在阿尔茨海默氏症协会国际会议之前。(C)2013年,阿尔茨海默氏症协会。All rights reserved.
Posterior cortical atrophy (PCA) is a clinicoradiologic syndrome characterized by progressive decline in visual processing skills, relatively intact memory and language in the early stages, and atrophy of posterior brain regions. Misdiagnosis of PCA is common, owing not only to its relative rarity and unusual and variable presentation, but also because patients frequently first seek the opinion of an ophthalmologist, who may note normal eye examinations by their usual tests but may not appreciate cortical brain dysfunction. Seeking to raise awareness of the disease, stimulate research, and promote collaboration, a multidisciplinary group of PCA research clinicians formed an international working party, which had its first face-to-face meeting on July 13, 2012 in Vancouver, Canada, prior to the Alzheimer's Association International Conference. (C) 2013 The Alzheimer's Association. All rights reserved.