One-pot synthesis of new symmetric and asymmetric xanthene dyes

One-pot synthesis of new symmetric and asymmetric xanthene dyes
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DOI:
10.1016/j.tetlet.2007.04.088
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发表时间:
2007-06-18
影响因子:
1.8
通讯作者:
Weissleder, Ralph
Weissleder, Ralph
中科院分区:
化学4区
文献类型:
--
作者:
Hilderbrand, Scott A.;Weissleder, Ralph

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使用浓磷酸作为溶剂,通过方便的一步程序从醛和二醇或间氨基苯酚前体制备对称和不对称呫吨染料。该协议提供了获得具有大斯托克位移和远红荧光发射的水溶性染料的途径。这些化合物被设想作为用于各种成像应用的荧光传感器的组件。 (c) 2007 Elsevier Ltd. 保留所有权利。
Symmetric and asymmetric xanthene dyes have been prepared by a convenient one-step procedure from aldehyde and diol or m-aminophenol precursors using concentrated phosphoric acid as a solvent. This protocol provides access to water-soluble dyes with large Stoke's shifts and far-red fluorescence emission. These compounds are envisioned as components of fluorescencebased sensors for a variety of imaging applications. (c) 2007 Elsevier Ltd. All rights reserved.