Childhood-onset schizophrenia: the challenge of diagnosis.
Childhood-onset schizophrenia: the challenge of diagnosis.
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DOI：
10.1007/s11920-011-0212-4
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发表时间：
2011-10
影响因子：
6.7
通讯作者：
Rapoport, Judith L.
中科院分区：
文献类型：
--
作者：
Gochman, Peter;Miller, Rachel;Rapoport, Judith L.
关键词：
在过去的20年里，国家精神卫生研究所的儿童精神病学分支对儿童期发作的精神分裂症（一种罕见的精神分裂症）进行了一项纵向研究（包括长期前瞻性随访）。这项研究的关键是准确的诊断。迄今为止，门诊筛查准确诊断了121名儿童期精神分裂症患者中的55%。然而，住院观察，包括无药物观察已被证明是至关重要的，以排除96名儿童的替代诊断谁已被临时住院研究。门诊筛查的标准化临床评分仅预测了62%的非精神分裂症患者。从历史上看，无药物观察是困难和不寻常患者的标准临床护理;在可能的情况下，应在类似情况下使用。
During the past two decades, the Child Psychiatry Branch at the National Institute of Mental Health has conducted a longitudinal study (including long-term prospective follow-up) of childhood-onset schizophrenia, a rare form of the disorder. Critical to this research has been accurate diagnosis. Outpatient screening has accurately diagnosed 55% of the 121 childhood-onset schizophrenia patients in the study to date. However, inpatient observation including drug-free observation has proven crucial to ruling out 96 children with alternative diagnoses who had been provisionally admitted for inpatient study. Standardized clinical ratings from outpatient screening only predicted 62% of these nonschizophrenia patients. Historically, medication-free observation was standard clinical care for difficult and unusual patients; this should be employed when possible in similar situations.
DOI：
10.1097/00004583-199406000-00003
发表时间：
1994-06-01
影响因子：
13.3
作者：
MCKENNA, K;GORDON, CT;RAPOPORT, JL
通讯作者：
RAPOPORT, JL
影响因子：
6.7
作者：
Rapoport, Judith L;Addington, Anjene;Frangou, Sofia
通讯作者：
Frangou, Sofia