PGEToolbox: A matlab toolbox for population genetics and evolution
PGEToolbox: A matlab toolbox for population genetics and evolution
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DOI：
10.1093/jhered/esm127
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发表时间：
2008-07-01
影响因子：
3.1
通讯作者：
Cai, James J.
中科院分区：
文献类型：
--
作者：
Cai, James J.
评估种群内的遗传多样性对于在分子水平上理解进化过程的性质至关重要。PGEM2.0是一个基于Matlab的开源软件包，用于群体遗传学数据分析。该软件的主要特点是：1）能够处理DNA序列多态性和单核苷酸多态性（SNPs），包括基因型和单倍型数据; 2）详尽的群体遗传分析和基于结合理论的中性检验; 3）可扩展性和可扩展性，适用于复杂和大型的全基因组数据集; 4）简单而有效的图形用户界面和复杂的数据和结果可视化。对于学术用途，PGElidine可在http://bioinformatics.org/pgetoolbox免费获得。
Assessing genetic diversity within populations is vital for understanding the nature of evolutionary processes at the molecular level. PGEToolbox is a Matlab-based open-sourced software package for data analysis in population genetics. The main features of this software are as follows: 1) capability for handling both DNA sequence polymorphisms and single nucleotide polymorphisms (SNPs), which include genotype and haplotype data; 2) exhaustive population genetic analyses and neutrality tests based on the coalescent theory; 3) extendibility and scalability for complex and large genome-wide datasets; 4) simple yet effective graphic user interfaces and sophisticated visualization of data and results. For academic uses, PGEToolbox is available free of charge at http://bioinformatics.org/pgetoolbox.