ANALYSIS OF 506 CONSECUTIVE POSITIVE SEROLOGIC TESTS FOR BRUCELLOSIS IN SAUDI-ARABIA

ANALYSIS OF 506 CONSECUTIVE POSITIVE SEROLOGIC TESTS FOR BRUCELLOSIS IN SAUDI-ARABIA
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DOI:
10.1128/jcm.25.8.1384-1387.1987
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发表时间:
1987-08-01
影响因子:
9.4
通讯作者:
KHAN, MY
KHAN, MY
中科院分区:
医学2区
文献类型:
--
作者:
KIEL, FW;KHAN, MY

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布氏杆菌病在沙特阿拉伯中部地区很常见。诊断的主要线索是血清学试验。在3年内,确定了超过500例滴度为1:160或更高的阳性患者,布鲁氏菌是所有血培养中最常见的单一微生物,在24%的病原菌培养阳性患者中发现。证实了预期的较高初始记录滴度的布鲁氏菌培养物数量; 31%的阳性高滴度组具有阳性布鲁氏菌培养物。结论性相关性在低于1:640滴度时并不常见。较低的滴度作为该人群中活动性疾病的指标不太有用,其中许多人似乎具有持续的低抗体水平。
Brucellosis is common in the central region of Saudi Arabia. The major clue to the diagnosis is serologic testing. In 3 years, over 500 positive patients who had a titer of 1:160 or more were identified, Brucella species was the single organism most commonly recovered in all blood cultures, being found in 24% of patients with cultures positive for pathogenic bacteria. The expected greater number of Brucella cultures with high initial recorded titer was confirmed; 31% of the positive high-titer group had positive Brucella cultures. Conclusive correlation was uncommon below the 1:640 titer. The lower titers were less useful as indicators of active disease in this population, in which many people appear to have persistent low antibody levels.