Lung Function Decline in Male Heavy Smokers Relates to Baseline Airflow Obstruction Severity
Lung Function Decline in Male Heavy Smokers Relates to Baseline Airflow Obstruction Severity
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DOI：
10.1378/chest.11-2837
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发表时间：
2012-12-01
期刊：
影响因子：
9.6
通讯作者：
Lammers, Jan-Willem J.
中科院分区：
文献类型：
--
作者：
Hoesein, Firdaus A. A. Mohamed;Zanen, Pieter;Lammers, Jan-Willem J.
背景：最近的证据表明，肺功能下降的速度在轻度COPD中最快，在中度至重度COPD中更慢。目前的研究评估了男性重度吸烟者肺功能下降是否与基线气流阻塞严重程度有关。方法：共有2003名平均（SD）年龄为59.8（5.3）岁的男性吸烟者在基线和3年随访后接受了肺功能检测。按入组FEV1/FVC分为：1组，bb0 ~ 70%；组2,
Background: Recent evidence indicates that the rate of lung function decline is steepest in mild COPD and slower in moderate to severe COPD. The current study assessed whether lung function decline relates to baseline airflow obstruction severity in male heavy smokers.Methods: In total, 2,003 male smokers with a mean (SD) age of 59.8 (5.3) years underwent pulmonary function testing at baseline and after 3-year follow-up. Participants were classified by entry FEV1/FVC as follows: group 1, >70%; group 2,