Lower systolic blood pressure is associated with greater mortality in people aged 85 and older
Lower systolic blood pressure is associated with greater mortality in people aged 85 and older
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DOI：
10.1111/j.1532-5415.2008.01948.x
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发表时间：
2008-10-01
影响因子：
6.3
通讯作者：
Gustafson, Yngve
中科院分区：
文献类型：
--
作者：
Molander, Lena;Lovheim, Hugo;Gustafson, Yngve
目的：研究老年人血压与死亡率之间的关系。设计：基于人群的队列研究。地点：瑞典Vasterbotten县。参与者：瑞典北部一个城市和五个农村自治市的所有85岁和所有90岁和95岁及以上的受试者（N = 348）的一半。测量：其中包括仰卧位血压、简易精神状态检查、日常生活活动的Barthel指数、简易营养评估和体重指数。收集诊断、药物和4年死亡率的信息。血压和死亡率之间的关联进行了调查，使用考克斯回归分析，控制了一些诊断和健康factors.Results：基线收缩压（SBP），舒张压，脉压均与死亡率在4年内，根据单变量分析呈负相关。SBP是最强的预测因子。在考克斯回归分析中，低SBP（
OBJECTIVES: To investigate the association between blood pressure and mortality in very old people.DESIGN: Population-based cohort Study.SETTING: County of Vasterbotten, Sweden.PARTICIPANTS: Half of all Subjects aged 85 and all of those aged 90 and 95 and older (N = 348) in one urban and five rural municipalities in the north of Sweden.MEASUREMENTS: Among others, supine blood pressure, Mini-Mental State Examination, Barthel Index of activities of daily living, Mini Nutritional Assessment, and body mass index. Information oil diagnoses, medications, and 4-year mortality was collected. Associations between blood pressure and mortality were investigated using Cox regression analyses, controlling for a number of diagnoses and health factors.RESULTS: Baseline systolic blood pressure (SBP), diastolic blood pressure, and Pulse pressure were all inversely associated with mortality within 4 years according to univariate analysis. SBP was the strongest predictor. In Cox regression analyses, low SBP (