Prevalence, treatment, and control of hypertension in chronic hemodialysis patients in the United States
Prevalence, treatment, and control of hypertension in chronic hemodialysis patients in the United States
复制标题
DOI：
10.1016/s0002-9343(03)00366-8
复制
发表时间：
2003-09-01
影响因子：
5.9
通讯作者：
Warnock, DG
中科院分区：
文献类型：
--
作者：
Agarwal, R;Nissenson, AR;Warnock, DG
背景技术背景：高血压是常见的慢性血液透析患者，但有有限的高血压的流行病学数据，这些患者在美国。方法：我们评估了高血压的患病率，治疗和控制在一个队列的2535临床稳定，成人血液透析患者谁参加了一个多中心研究的安全性和耐受性的静脉注射铁制剂。高血压定义为平均透析前收缩压> 150 mm Hg或舒张压>85 mm Hg，或使用抗高血压药物。高血压的患病率，与一般人群中观察到的情况相反，并没有随着年龄的线性增长，也没有受到性别或种族的影响。仅30%（n = 659）的高血压患者的高血压得到充分控制。在其余患者中，高血压未治疗（12% [252/2173]）或治疗不充分（58% [1262/2173]）。结论：控制高血压，特别是收缩期高血压，在美国的慢性血液透析患者是不够的，尽管认识到其患病率和频繁使用抗高血压药物。优化药物的使用和密切关注非药物干预，如调整干体重，低钠饮食和运动，可能会改善控制。(C)2003年，Excerpta Medica Inc.
BACKGROUND: Hypertension is common in chronic hemodialysis patients, yet there are limited data on the epidemiology of hypertension in these patients in the United States.METHODS: We assessed the prevalence, treatment, and control of hypertension in a cohort of 2535 clinically stable, adult hemodialysis patients who participated in a multicenter study of the safety and tolerability of an intravenous iron preparation. Hypertension was defined as an average predialysis systolic blood pressure > 150 mm Hg or diastolic blood pressure >85 mm Hg, or the use of antihypertensive medications.RESULTS: Hypertension was documented in 86% (n = 2173) of patients. The prevalence of hypertension, in contrast to that observed in the general population, did not increase linearly with age and was not affected by sex or ethnicity. Hypertension was controlled adequately in only 30% (n = 659) of the hypertensive patients. In the remaining patients, hypertension was either untreated (12% [252/2173]) or treated inadequately (58% [1262/2173]).CONCLUSION: Control of hypertension, particularly systolic hypertension, in chronic hemodialysis patients in the United States is inadequate, despite recognition of its prevalence and the frequent use of antihypertensive drugs. Optimizing the use of medications and closer attention to nonpharmacologic interventions, such as adjustment of dry weight, a low-sodium diet, and exercise, may improve control. (C) 2003 by Excerpta Medica Inc.