Genetic and environmental influences on finger-sucking and nail-biting in Japanese twin children
Genetic and environmental influences on finger-sucking and nail-biting in Japanese twin children
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DOI：
10.1375/1832427054936637
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发表时间：
2005-08-01
影响因子：
0.9
通讯作者：
Ooki, S
中科院分区：
文献类型：
--
作者：
Ooki, S
这项研究的目的是利用日本双胞胎的最大数据库来阐明儿童时期吮手指和咬指甲的遗传因素。研究对象为 1131 对 12 岁双胞胎儿童，其中男性 1057 名，女性 1205 名。所有数据均通过母亲问卷收集，并在医学访谈中检查对问卷的答复。 0 至 2 岁之间吸手指的患病率男性为 40%，女性为 43% (p = .0053)。 12 岁之前咬指甲的患病率男性为 28%，女性为 26%（不显着）。无论性别组合如何，同卵配对的一致性率和多向相关性均高于双卵配对。使用结构方程模型进行单变量和双变量遗传分析。结果显示，由于遗传影响而导致的总表型变异比例中，男性吸手指的比例为 66%，女性为 50%，而咬指甲的男性和女性的比例均为 50%。 17.7% 的男性（四向相关性：r = .40）和 15.7% 的女性（r = .32）同时出现吮手指和咬指甲行为，这部分归因于共同的遗传或环境因素。由遗传因素解释的总共享方差比例为 67%。
The purpose of this study was to clarify the genetic contribution to finger-sucking and nail-biting in childhood using the largest databases available on Japanese twins. The subjects were 1131 pairs of 12-year-old twin children, consisting of 1057 males and 1205 females. All data were gathered by maternal questionnaire, and responses to the questionnaire were checked in the medica interview. The prevalence of finger-sucking between 0 to 2 years was 40% in males and 43% in females (p = .0053). The prevalence of nail-biting up until the age of 12 years was 28% in males and 26% in females (nonsignificant). Concordance rates and polychoric correlations were all higher in monozygotic pairs than in dizygotic pairs, irrespective of the sex combination. Univariate and bivariate genetic analyses using structural equation modeling was performed. The results showed that the proportion of total phenotypic variance attributable to genetic influences was 66% in males and 50% in females for finger-sucking, and 50% in both males and females for nail-biting. A co-occurrence of finger-sucking and nail-biting was observed in 17.7% of males (tetrachoric correlation: r = .40) and 15.7% of females (r = .32), which was attribute partly to common genetic or environmental factors The proportion of total shared variance explained by genetic factors was 67%.