Fatigue after treatment for early stage breast cancer - A controlled comparison
Fatigue after treatment for early stage breast cancer - A controlled comparison
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DOI：
10.1002/cncr.22993
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发表时间：
2007-10-15
期刊：
影响因子：
6.2
通讯作者：
Andrykowski, Michael A.
中科院分区：
文献类型：
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作者：
Jacobsen, Paul B.;Donovan, Kristine A.;Andrykowski, Michael A.
背景有证据表明，对于癌症幸存者来说，疲劳可能比没有癌症的人更严重。本研究旨在确定相对于人口统计学匹配的无癌症史的女性对照组，完成早期乳腺癌治疗的女性是否更疲劳。作为一项大型研究的一部分，在开始化疗和放疗（n = 100）或仅放疗（n = 121）之前招募了0-II期乳腺癌女性。在治疗结束时以及2、4和6个月后评估疲劳。招募了一组年龄和地理位置匹配的无癌症史的女性样本，并进行了比较评估。相对于对照组，乳腺癌幸存者在过去一周的所有4项研究评估中报告了更多的疲劳天数（P
BACKGROUND. Evidence suggests that fatigue may be a greater problem for cancer survivors than people without cancer. The present study sought to determine whether fatigue was greater in women who had completed treatment for early-stage breast cancer relative to a demographically matched comparison group of women with no cancer history.METHODS. As part of a larger study, women with stage 0-II breast cancer were recruited before the start of chemotherapy and radiotherapy (n = 100) or radiotherapy only (n = 121). Fatigue was assessed at the end of treatment and 2, 4, and 6 months later. An age- and geographically matched sample of women with no history of cancer was recruited and assessed for comparison purposes.RESULTS. Relative to comparison subjects, breast cancer survivors reported more days of fatigue in the past week at all 4 study assessments (P