Idiosyncratic and systematic aspects of spatial representations in the macaque parietal cortex
Idiosyncratic and systematic aspects of spatial representations in the macaque parietal cortex
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DOI：
10.1073/pnas.0913209107
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发表时间：
2010-04-27
影响因子：
11.1
通讯作者：
Snyder, Lawrence H.
中科院分区：
文献类型：
--
作者：
Chang, Steve W. C.;Snyder, Lawrence H.
视觉引导到达的感觉运动转换最初被认为是在从一个系统参照系到下一个系统参照系的一系列离散转换中发生的，神经元在枕区和顶后区编码相对于注视位置(凝视中心)的位置，在背侧运动前皮质相对于肩部编码位置，在运动输出神经元中以基于肌肉或关节的坐标编码。最近的经验和理论工作表明，使用一系列特殊表征的空间编码可能会增加计算能力和灵活性。我们现在表明，顶叶前区的神经元使用非均匀和特殊的参照系。我们还表明，这些非系统参考系与系统复合增益场共存，该系统复合增益场与眼睛和手之间的距离成正比地调制活动。因此，系统信号和特殊信号可能在单个神经元中共存。
The sensorimotor transformations for visually guided reaching were originally thought to take place in a series of discrete transitions from one systematic frame of reference to the next with neurons coding location relative to the fixation position (gaze-centered) in occipital and posterior parietal areas, relative to the shoulder in dorsal premotor cortex, and in muscle- or joint-based coordinates in motor output neurons. Recent empirical and theoretical work has suggested that spatial encodings that use a range of idiosyncratic representations may increase computational power and flexibility. We now show that neurons in the parietal reach region use nonuniform and idiosyncratic frames of reference. We also show that these nonsystematic reference frames coexist with a systematic compound gain field that modulates activity proportional to the distance between the eyes and the hand. Thus, systematic and idiosyncratic signals may coexist within individual neurons.