Acylated triterpenoid saponins from the stem bark of Foetidia africana.
Acylated triterpenoid saponins from the stem bark of Foetidia africana.
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来自非洲 Foetidia africana 茎皮的酰化三萜皂苷。
DOI：
10.1021/np020151a
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发表时间：
2002
影响因子：
5.1
通讯作者：
C. Lavaud
中科院分区：
文献类型：
--
作者：
Marie;Isabelle Pouny;C. Delaude;C. Lavaud
从非洲 Foetidia africana 的茎皮中分离得到 9 个新的酰化三萜皂苷 (4-12)。它们都具有作为糖苷配基的barringtogenol C，被乙酸和/或异戊酸酯化。糖链最多由三个单元组成：D-葡萄糖醛酸 (GlcUA) 连接到糖苷配基的 C-3，并被 D-半乳糖 (Gal)（在 GlcUA C-2 处）和/或 L-鼠李糖 (Rha)（在 GlcUA C-4 处）取代。通过酸和碱水解、NMR 实验（包括 (1)H-(1)H (COSY、HOHAHA、ROESY) 和 (1)H-(13)C (HSQC、HMBC) 光谱）以及质谱 (ESIMS、ESIMS(n)) 确定结构。
Nine new acylated triterpenoid saponins (4-12) were isolated from the stem bark of Foetidia africana. They all possess barringtogenol C as the aglycone, esterified by acetic and/or isovaleric acids. The sugar chain consists of up to three units: D-glucuronic acid (GlcUA) linked to C-3 of the aglycone and substituted by D-galactose (Gal) (at GlcUA C-2) and/or L-rhamnose (Rha) (at GlcUA C-4). The structures were established by acid and alkaline hydrolysis, by NMR experiments including (1)H-(1)H (COSY, HOHAHA, ROESY) and (1)H-(13)C (HSQC, HMBC) spectroscopy, and by mass spectrometry (ESIMS, ESIMS(n)).