Optoacoustic tomography using time-resolved interferometric detection of surface displacement.
Optoacoustic tomography using time-resolved interferometric detection of surface displacement.
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DOI：
10.1117/1.1559727
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发表时间：
2003-04
影响因子：
3.5
通讯作者：
B. Payne;V. Venugopalan;B. Mikić;N. Nishioka
中科院分区：
文献类型：
--
作者：
B. Payne;V. Venugopalan;B. Mikić;N. Nishioka
我们介绍了一种微创技术的混浊介质的光声成像，利用光学干涉检测的表面位移产生的热弹性应力瞬态。该技术利用异质组织的内源性或外源性光学对比度和应力波传播的低衰减来定位和成像光学混浊介质中的表面下吸收体。我们提出了一个系统，利用一个时间分辨的高分辨率干涉仪能够埃级的位移分辨率和纳秒时间分辨率，以检测模型组织幻影和人体前臂内的皮下血管在体内。
We introduce a minimally invasive technique for optoacoustic imaging of turbid media using optical interferometric detection of surface displacement produced by thermoelastic stress transients. The technique exploits endogenous or exogenous optical contrast of heterogeneous tissues and the low attenuation of stress wave propagation to localize and image subsurface absorbers in optically turbid media. We present a system that utilizes a time-resolved high-resolution interferometer capable of angstrom-level displacement resolution and nanosecond temporal resolution to detect subsurface blood vessels within model tissue phantoms and a human forearm in vivo.