Prevalence of antibody to HTLV-III/LAV in a population attending a sexually transmitted diseases clinic.
Prevalence of antibody to HTLV-III/LAV in a population attending a sexually transmitted diseases clinic.
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去性传播疾病诊所就诊的人群中 HTLV-III/LAV 抗体的患病率。
DOI：
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发表时间：
1987
影响因子：
3.1
通讯作者：
S. Schultz
中科院分区：
文献类型：
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作者：
C. Rabkin;P. Thomas;H. Jaffe;S. Schultz
为了确定HTLV-III/LAV是否通过异性接触传播给男性，以及与妓女的接触是否在这种传播中起作用，在纽约市的性传播疾病诊所进行了血清调查。295名男性异性恋非使用者的静脉注射药物进行了研究。在10名男性（3.4%）的血清中发现了HTLV-III/LAV抗体;这一比率约为健康献血者中发现的流行率的15倍。血清阳性与梅毒（比值比，11.2; 95%置信区间，2.1-52）和B型肝炎感染（比值比，9.1; 95%置信区间，2.0-55）的血清学证据相关。HTLV-III/LAV抗体与自我报告的妓女暴露无关（比值比，0.8; 95%置信区间，0.08-4.2）。这些研究结果表明，HTLV-III/LAV的异性性传播给男人，但没有牵连与妓女的接触，这种传播方式。
To determine whether HTLV-III/LAV is transmitted to men by heterosexual contact and whether contact with prostitutes plays a role in such transmission, a serosurvey was conducted in clinics for sexually transmitted diseases in New York City. Two hundred ninety-five male heterosexual nonusers of intravenous drugs were studied. Antibody to HTLV-III/LAV was found in sera from ten men (3.4%); this rate is approximately 15 times the prevalence found in healthy blood donors. Seropositivity was associated with serologic evidence of syphilis (odds ratio, 11.2; 95% confidence interval, 2.1-52) and hepatitis B infection (odds ratio, 9.1; 95% confidence interval, 2.0-55). Antibody to HTLV-III/LAV was not associated with self-reported exposure to prostitutes (odds ratio, 0.8; 95% confidence interval, 0.08-4.2). These findings suggest heterosexual transmission of HTLV-III/LAV to men but fail to implicate contact with prostitutes as a mode of such transmission.