tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences
tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences
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DOI:
10.1007/978-1-4939-9173-0_1
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发表时间:
2019-01-01
期刊:
影响因子:
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通讯作者:
Lowe, Todd M.
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文献类型:
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作者:
Chan, Patricia P.;Lowe, Todd M.
Transfer RNAs are the largest, most complex non-coding RNA family, universal to all living organisms. tRNAscan-SE has been the de facto tool for predicting tRNA genes in whole genomes. The newly developed version 2.0 has incorporated advanced methodologies with improved probabilistic search software and a suite of new gene models, enabling better functional classification of predicted genes. This chapter describes the use of the UNIX command-driven and online web versions, illustrating different search modes and options.